Lexington is the county seat of Davidson County, North Carolina, United States. As of the 2010 census, the city had a population of 18,931. It is located in central North Carolina, 20 miles south of Winston-Salem. Major highways include I-85, I-85B, U.S. Route 29, U.S. Route 70, U.S. Route 52 and U.S. Route 64. Lexington is part of the Piedmont Triad region of the state.Lexington, Thomasville, and the rural areas surrounding them are slowly developing as residential bedroom communities for nearby cities such as Winston-Salem, Greensboro and High Point.